Manual of Pharmacodynamics

Manual of Pharmacodynamics

  • Richard Hughes, MD


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Hughes was an impeccable scholar who lectured on materia medica to the British Homoeopathic Society in London.

These are the transcriptions of his lectures.

962 pp hb

From the Book

The book is in form of lectures on the remedies, which are presented in a personal fashion but carefully and succinctly stating the history of the drug source, its use, its abuse, its preparation, etc.


1 - Introduction -- 1-16
2 - Sources of the Homeopathic Materia Medica -- 17-39
3 - Sources (continued) -- 40-53
4 - The General Principles of Drug-action -- 54-67
5 - The General Principles of Drug-action (continued) -- 68-78
6 - Homeopathy - What it is -- 79-92
7 - Homeopathic Posology -- 93-106
8 - Acidum Benzoicum, Carbolicum, Fluoricum, Hydrocyanicum, Muriaticum -- 107-123
9 - Acidum Nitricum, Oxalicum, Phosphoricum, Picricum, Salicylicum, Sulphuricum -- 124-146
10 - Aconite -- 147-166
11 - Actea, Esculus, Ethusa, Agaricus, Agnus Castus, Ailanthus -- 167-182
12 - Allium Cepa and Sativum, Aloes, Alumen, Alumina, Ambra, Ammonium Carbonicum and Muriaticum, Amyl Nitrite, Anacardium, Augustura -- 183-197
13 - Antimonium Crudum and Tartaricum, Apocynum -- 198-211
14 - Apis, Argentum Metallicum, and Nitricum -- 212-227
15 - Arnica, Arsenic -- 228-246
16 - Arsenic (continued) -- 247-263
17 - Arum, Asafoetida, Asarum, Asclepias, Asterias, Aurum, Baptisia -- 264-280
18 - Baryta, Belladonna -- 281-294
19 - Belladonna (continued) -- 295-307
20 - Berberis, Bismuth, Borax, Bovista, Bromine and the Bromides -- 308-322
21 - Bryonia -- 323-335
22 - Cactus, Calcarea -- 336-348
23 - Calendula, Camphor, Cannabis Sativa, and Indica, Cantheris -- 349-364
24 - Capsicum, Carbon Sulphuratum, Carbo Animalis and Vegetabilis, Caulophyllum. Causticum, Cedron -- 365-377
25 - Chamomilla, Chelidonium, Chimphila, Chloral, Chlorum, Cicuta, Cina and Santonine -- 378-390
26 - Cinchona -- 391-408
27 - Cinchona Alkaloids, Cistus, Clematis, Coca, Cocculus, Coccus Cacti, Coffea -- 409-424
28 - Colchicum, Collinsonia, Colocynth, Conium, Copaiba -- 425-441
29 - Corallium, Crocus, Croton, Cundurango, Cuprum, Curare, Cyclamen, Dioscorea -- 442-456
30 - Digitalis, Drosera -- 457-470
31 - Dulcamara, Elaterium, Eupatorium Perfoliatum and Pnrpureum, Euphorbium, Euphrasia, Ferrum -- 471-487
32 - Gamboge, Gelsemium, Glonoin, Graphites, Gratiola, Guaiacum -- 488-504
33 - Hamamelis, Helleborus, Helonias, Hepar Sulphuris -- 505-519
34 - Hydrastis, Hydrocotyle, Hyoscyamus, Hypericum, Indigo -- 520-533
35 - Ignatia, Iodine, and the Iodides -- 534-546
36 - Iodine and the Iodides (continued), Iris -- 547-562
37 - Ipecacuanha, Jaborandi, Kali Bichromicum -- 563-579
38 - Kali Carbonicum, Chloricum, Nitricum and Permanganicum, Kalmia, Kreosote, Lactuca -- 580-594
39 - Lachesis and the Serpent-Poisons -- 595-608
40 - Ledum, Leptandra, Lilium, Lithium, Lobelia, Lycopodium, Lycopus -- 609-623
41 - Mercurius -- 624-635
42 - Mercurius (continued) -- 636-648
43 - Mercurius (continued) -- 649-664
44 - Magnesia Carbonica and Muriatica, Manganum, Menyanthes, Mezereum, Millefolium, Moschus, Murex, -- Natrum Carbonicum, Muriaticum, and Sulphuricum, Nuphar -- 665-681
45 - Nux Vomica -- 682-694
46 - Nux Moschata, Enanthe, Oleander, Opium -- 695-710
47 - Opium Alkaloids, Origanum, Osmium, Paeonia, Paris, Petroleum, Petroselinum, Phellandrium, -- Physostigma, Phytolacca -- 711-725
48 - Phosphorus -- 726-740
49 - Phosphorus (continued), Plumbum -- 741-758
50 - Platina, Podophyllum, Pulsatilla -- 759-774
51 - Ranunculus, Ratanbia, Rheum, Rhododendrum, Rhus, Rumex, Ruta -- 775-790
52 - Sabadilla, Sabina, Sambucus, Sanguinaria, Sarrancenia, Sarsaparilla, Scilla, Secale, Selenium, Senega -- 791-806
53 - Sepia, Silica -- 807-821
54 - Spigelia, Spongia, Stannum, Staphisagria, Stramonium -- 822-836
55 - Sulphur -- 837-849
56 - Tabacum, Taraxacum, Tellurium, Terebinthina, Teucrium, Thuja, Uranium -- 850-868
57 - Urtica, Uva Ursi, Valerian, Veratrum Album and Viride, Verbascum, Viola Odorata and Tricolor, Xanthoxylum, Zincum -- 869-885

Supplementary -- 886-929
Appendix -- 930-939
Index of Medicines -- 940-943
Clinical Index -- 944-962

Dr. Richard Hughes

(1836 - 1902)

Dr. Richard Hughes was born in London, England. He received the title of M.R.C.S. (Eng.), in 1857 and L.R.C.P. (Edin.) in 1860. The title of M.D. was conferred upon him by the American College a few years later.

Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English.

In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise.

In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.


A transcription of the lectures on materia medica delivered to his classes in London.

Although much of the material in the book concerns the pharmacological action of the remedies, Hughes' scholarship is flawless. He says this work is "in no way a substitute for the materia medica. It is, rather, a guide and companion to it."

The back of the book has a remedy index with clinical indications listed. The book was issued by William Radde in 1868, and had its 5th edition in the UK in 1886.

Julian Winston writes:
George Royal relates that he was told by his preceptor to study Hering's Condensed Materia Medica, but he couldn't make head nor tail of it.

He then met Erastus Case who said,
"That foolish man! Why did he not give you Hughes' Pharmacodynamics first? Get that and read it through. Then you can appreciate Hering."

Although Kent considered Hughes a "skunk" for the emphasis on the pathological symptoms and advocacy of substantial doses, the book by Hughes is one of the best essays in the basics of homeopathic materia medica.

However it should be kept in mind that Hughes was concerned with the pathological symptoms seen in the provings and many of our most "characteristic symptoms" we find in discussing remedies today will not be found in Hughes' work. Many of them developed through clinical symptoms after this work was published, and many Hughes would disregard because they are not in the provings.

Said Dr. Fornias in the April 1888 issue of The Medical Advance:
"It is a book written in elegant, forcible English, well adapted to inveigle or induce our old-school friends to look into the contains information well to know, but I pity the Homeopathist who goes into the sick-chamber provided only with the limited knowledge of symtomatology which can be obtained from this book."

Says H.C. Allen, of the book,
"It teaches us how to practice Allopathy with homeopathic remedies. Nothing more. The prescriber is taught to guess both at the pathology of the disease and the pathological action of the remedy, but he can never make an accurate Homeopathic prescription if he follows its teaching. Is it to not be wondered at that 'our old-school friends' are often disappointed?"

The Heritage of Homoeopathic Literature
copyright 2001 by Julian Winston
Reprinted with the permission of the author